The infamous San Andreas Fault gives way, producing a devastating earthquake across California. A highly skilled helicopter pilot (Dwayne Johnson) races to save his ex-wife (Carla Gugino) in Los Angeles before the complete destruction of the city. After one daring rescue, the pilot flies north toward San Francisco in search of his estranged daughter (Alexandra Daddario), racing against time and the inevitable aftershocks that promise to devastate the coastline.